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The organic salt tetra butyl ammonium fluoride trihydrate (TBAF3H2O) has the chemical formula (C4H9)4NF3H2O. At ambient temperature, it is a white, crystalline solid that is frequently employed as a source of fluoride ions in a variety of chemical processes.

The quaternary ammonium salt known as TBAF is very soluble in polar organic solvents and water. It is frequently employed in organic synthesis as a moderate and selective fluorinating reagent, particularly in the deprotection of various protective groups like silyl ethers and acetals.

Additionally, the natural product and pharmaceutical TBAF has been employed in the production of Taxol, an anti-tumor agent. TBAF has also been utilised to functionalize a variety of materials, including the production of self-assembled monolayers and the alteration of carbon nanotubes.

However, due to its high alkalinity and propensity for toxicity when consumed or inhaled, TBAF can be dangerous. When handling TBAF, proper safety procedures should be followed, including the use of protective gear and sufficient ventilation.

Overall, TBAF is a helpful and adaptable reagent in organic synthesis and materials research, but due to its possible risks, care should be taken when handling it.
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