Pentamethonium Dibromide

Pentamethonium Dibromide

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Product Description

Pentamethonium dibromide is a quaternary ammonium compound that acts as a ganglionic blocker. It is a salt consisting of two bromide anions and one pentamethonium cation. Its chemical formula is C21H38Br2N2.

Pentamethonium dibromide was once used as a medication to lower blood pressure by blocking the transmission of nerve impulses to the heart and blood vessels. However, it is no longer commonly used due to the availability of more effective and safer medications for treating hypertension.

The compound is a white crystalline powder that is highly soluble in water and has a bitter taste. It is classified as a schedule II controlled substance in the United States due to its potential for abuse and dependence.

As with other quaternary ammonium compounds, pentamethonium dibromide should be handled with care due to its potential for skin and eye irritation. It should also be stored in a cool, dry place away from sources of ignition and incompatible materials.


1. What is pentamethonium dibromide?

Ans - Pentamethonium dibromide is a synthetic organic compound used as a muscle relaxant. It is used to treat spasms and muscle pain caused by conditions such as multiple sclerosis and spinal cord injuries.

2. How does pentamethonium dibromide work?

Ans - Pentamethonium dibromide works by blocking the transmission of nerve impulses along nerve endings, thus preventing the muscles from contracting.

3. What are the side effects of pentamethonium dibromide?

Ans - Possible side effects of pentamethonium dibromide include nausea, vomiting, dizziness, dry mouth, constipation, and blurred vision.

4. Who should not take pentamethonium dibromide?

Ans - Pentamethonium dibromide should not be taken by those with certain medical conditions, such as heart disease, kidney disease, or liver disease. It should also not be taken by pregnant or breastfeeding women.

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